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Old 01-13-2024, 08:02 PM
  #11  
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Originally Posted by AirportJunkie
And yet you continue sit there and wonder why your neighbors cheered, jeez you people are some SERIOUS dumb MFers.
Whether you get it from a vaccine or an infection, COVID-19 immunity does not last forever. In a study published May 3 in JAMA Network Open, researchers combed through studies to determine just how long protection from the shots endures.

The scientists, led by a team from Italy, analyzed 40 studies that documented people’s vaccination status and their subsequent infections with COVID-19, confirmed by lab tests. The studies included data from both the Delta and Omicron surges.

Overall, the researchers found that one month after people received two doses of either mRNA vaccine (from Moderna or Pfizer-BioNTech), the vaccine from AstraZeneca, or the shot from Sinovac, the vaccine effectiveness was 53% in protecting against symptoms of COVID-19. (There were differences among the vaccines, with Moderna’s primary series of two shots showing the highest effectiveness of 62% one month after the series, and Sinovac’s demonstrating the lowest effectiveness at 32%.) After six months, the overall effectiveness of the vaccines dropped further to 14%, and to 9% after nine months. This waning was greater during the Omicron wave than during the Delta wave, suggesting that the vaccine was less effective against Omicron.

Booster doses after the primary series restored protection back to levels achieved just after the primary vaccination, but this protection waned too, at a rate similar to that after the primary series, dropping from 60% at one month after the booster dose to 13% at nine months. This drop in efficacy corresponded to rates of lab-confirmed positive tests for Delta and Omicron infections.
There's the science for you. Are you educated enough to understand the implications of this?

if you really want the facts, here is a New England Journal of Medicine article for yiur review:

https://www.nejm.org/doi/full/10.1056/nejmoa2116597

If it's too technical for you, I'll extract the Cliff's Notes version for you:

Among 146,243 tested contacts of 108,498 index patients, 54,667 (37%) had positive SARS-CoV-2 polymerase-chain-reaction (PCR) tests. In index patients who became infected with the alpha variant, two vaccinations with either BNT162b2 or ChAdOx1 nCoV-19 (also known as AZD1222), as compared with no vaccination, were independently associated with reduced PCR positivity in contacts (adjusted rate ratio with BNT162b2, 0.32; 95% confidence interval [CI], 0.21 to 0.48; and with ChAdOx1 nCoV-19, 0.48; 95% CI, 0.30 to 0.78). Vaccine-associated reductions in transmission of the delta variant were smaller than those with the alpha variant, and reductions in transmission of the delta variant after two BNT162b2 vaccinations were greater (adjusted rate ratio for the comparison with no vaccination, 0.50; 95% CI, 0.39 to 0.65) than after two ChAdOx1 nCoV-19 vaccinations (adjusted rate ratio, 0.76; 95% CI, 0.70 to 0.82). Variation in cycle-threshold (Ct) values (indicative of viral load) in index patients explained 7 to 23% of vaccine-associated reductions in transmission of the two variants. The reductions in transmission of the delta variant declined over time after the second vaccination, reaching levels that were similar to those in unvaccinated persons by 12 weeks in index patients who had received ChAdOx1 nCoV-19 and attenuating substantially in those who had received BNT162b2. Protection in contacts also declined in the 3-month period after the second vaccination.
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Old 01-13-2024, 08:04 PM
  #12  
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Originally Posted by Excargodog
There's the science for you. Are you educated enough to understand the implications of this?

if you really want the facts, here is a New England Journal of Medicine article for yiur review:

https://www.nejm.org/doi/full/10.1056/nejmoa2116597

If it's too technical for you, I'll extract the Cliff's Notes version for you:
The problem with your data is that it excludes the healing powers of Scott Kirby. One touch and your neighbor will be saved.
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Old 01-13-2024, 08:09 PM
  #13  
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If there's a bright side to decreasing vaccine effectiveness with time, it's most definitely catching COVID, dying, and thus no longer seeing endless rehashed arguments about it.
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Old 01-13-2024, 08:49 PM
  #14  
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Originally Posted by AirportJunkie
Deleted, no point in arguing with village idiots.
The ignore function in your user control works spectacularly well.

Anyone stupid enough to visib breitbart deserves to believe in the conspiracy theories. It's a lot like a dog endlessly entertained by chasing its own tail.

The antivaccination conspiracy crowd is remarkly similar to the primates frightened and angered by the monolith at the outset of 2001 Space Odessy. Ignorant, and uninformed, and terrified of what they don't understand.

https://youtu.be/cHWs3c3YNs4?si=IOUTgnxHVNbuwfOa
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Old 01-13-2024, 09:15 PM
  #15  
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Originally Posted by CLazarus
If there's a bright side to decreasing vaccine effectiveness with time, it's most definitely catching COVID, dying, and thus no longer seeing endless rehashed arguments about it.
Except you are less susceptible to damage with past exposure, either from vaccines or from just catching it. It was big news when it was a NOVEL coronavirus. Eventually it'll likely be no more pathogenic than the other four human coronaviruses we've been getting all our lives.

  1. 229E (alpha coronavirus)
  2. NL63 (alpha coronavirus)
  3. OC43 (beta coronavirus)
  4. HKU1 (beta coronavirus)
https://www.cdc.gov/coronavirus/types.html

https://www.cdc.gov/coronavirus/general-information.html
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Old 01-13-2024, 10:27 PM
  #16  
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Originally Posted by AirportJunkie
Funny how the 10 commandments mentions love thy neighbor, yet you religious wanna bes could care less about your neighbors.

It’s not surprising that the neighbors cheered.
10 commandment does not mention love thy neighbor. One might make the case with 6 degrees of Kevin Bacon, but I don't recall ever seeing that.
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Old 01-13-2024, 11:29 PM
  #17  
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Originally Posted by AirportJunkie
Funny how the 10 commandments mentions love thy neighbor, yet you religious wanna bes could care less about your neighbors.

It’s not surprising that the neighbors cheered.
*Could not*, my lovely neighbor.

Assumptions you make.
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Old 01-14-2024, 12:28 PM
  #18  
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Originally Posted by Excargodog;[url=tel:3751329
3751329[/url]]It's interesting to compare what Fauci said then with what he now claims he said then. And the actual effectiveness and longevity of COVID immunizations with what it was originspally claimed they Woukd do.

Don't get me wrong, for those at serious risk, it was unequivocally a good thing to have their first exposure to COVID-19 be through immunization, b.
Except, unlike all previous (true) vaccines, it did not provide any "exposure". The stated design was to weaken one's own immune response to the virus. Turns out it didn't prevent most people from contracting it... or..later, .Fauci-ites then shifted their position to "lessening the effects"...
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Old 01-16-2024, 03:05 PM
  #19  
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Originally Posted by hopp
Except, unlike all previous (true) vaccines, it did not provide any "exposure". The stated design was to weaken one's own immune response to the virus. Turns out it didn't prevent most people from contracting it... or..later, .Fauci-ites then shifted their position to "lessening the effects"...
It did prevent infection, for the original variant for a period of time.

It still does vastly reduce the likelyhood of severe covid.

I'm no fan of the .gov behavior during the pandemic but those are both facts.
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Old 01-17-2024, 04:56 AM
  #20  
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Originally Posted by rickair7777
It did prevent infection, for the original variant for a period of time.

It still does vastly reduce the likelyhood of severe covid.

I'm no fan of the .gov behavior during the pandemic but those are both facts.
Agreed, although it was a very short period of time.

I've repeatedly said that for those at real risk (basically middle age adults and older unless there were special risk factors involved) immunization was your safest way to get an initial exposure) but with the logistics of a mass immunization that initially did first target the elderly, by the time they got around to targeting the general population the protection of the first group had already waned. It saved them from severe disease but not from getting the disease. And by the time the deadlines on mandatory vaccination expired by the younger groups (as in the uniformed services) most of them had already survived one or more infections already and except for the I-gave-you-a legal-order-mister issue going after those not yet vaccinated really didn't make sense, their already low susceptibility to serious disease had already saved with their exposure naïveté.

What irritates the hell out of me was that by that time we already knew the age related pathogenicity curve of the illness from the early Spanish and Italian outbreaks data where 50% of mortality was in the 85 year old and over age group. The CDC HAD THAT DATA and routinely collect such data in the US as well WHICH UNLIKE FOR PREVIOUS DECADES THEY STOPPED PUBLISHING. Whether that was someone's idea to encourage immunization or if they just sent those people home and were unable to continue disseminating it or those people got redistributed to some other job I have no idea, but the statistics af lethality related to age were known overseas early on.

Also known early on - from the beginning really - was the quick waning of protection from reinfection after initial immunization with corronavirus immunizations - not just with the initial strain but with coronaviruses in general. There are a number of veterinary coronavirus vaccines on the market that are useful because you can vaccinate the whole herd simultaneously which is commercially helpful if you are protecting a herd of animals although none protect from reinfection for very long, dropping back to full susceptibility by nine months. Similar relatively brief immunity to reinfection after exposure to the four commonly circulating human coronaviruses is seen, with susceptibility to reinfection occurring quickly - 50% can be reinfected within three months.

What made sense and saved the most lives was immunizing the elderly and at high risk first but it was never going to stop the epidemic from burning itself out because worldwide immunization within the timeframe of immunity from reinfection of the initially vaccinated group was logistically impossible. Hell, 20% of the world's population have STILL not had immunizations and many who have been immunized have been immunized with Sinovax which wasn't terribly effective to begin with.

Treating those people who failed to get vaccinated - either because of fear, misinformation, religious belief, or simple ignorance as some sort of traitor to the human race or potential Typhoid Mary was never warranted. And doing so after the most vulnerable were already protected and most of the antivaxxers had already had the disease anyway wasn't science, it was just an abuse of the police power of the state. But the real harm was what the shutdowns did to the educational status of the kids - which is well documented - and to other branches of preventative medicine.

When you stop doing Pap smears, mammograms, and screening sigmoidoscopies for a year, those cancers don't stop happening. They are just detected later - at more advanced stages and in greater numbers, overtaxing the facilities that treat them and giving people poorer outcomes.

Thise were not just a predictable result of the shutdowns, they were a predicted result of the shutdowns. We did it anyway. And the arrogance and incompetence with which it was done (do you recall New York and New Jersey MANDATING that nursing homes full of the most susceptible people take in known actively contagious COVID patients to free up hospital space?) only created more antivaxxers and fed into conspiracy theories.

For the next 100 years this is going to be taught in graduate schools as the way to NOT handle a pandemic.
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