Covid Treatment Development
12-09-2021, 12:30 PM
#31
Gets Weekends Off
Joined APC: Oct 2006
Position: Dream Job
Posts: 403
https://www.newsnationnow.com/health...body-cocktail/
FDA approves AstraZeneca MCA cocktail.
It's actually not approved for use as a therapy, but rather a preventive in lieu of vaccines. Useful for those with compromised immune systems, or vaccine allergies. Protection for several months to one year, didn't mention what the efficacy is. Not sure it's available for anti-vaxxers, may need some medical history.
FDA approves AstraZeneca MCA cocktail.
It's actually not approved for use as a therapy, but rather a preventive in lieu of vaccines. Useful for those with compromised immune systems, or vaccine allergies. Protection for several months to one year, didn't mention what the efficacy is. Not sure it's available for anti-vaxxers, may need some medical history.
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12-14-2021, 05:44 PM
#33
Perennial Reserve
Joined APC: Jan 2018
Posts: 12,200
FRANKFURT (Reuters) - German researchers have found that COVID-19 therapies developed by Eli Lilly and Regeneron lose most of their effectiveness when exposed in laboratory tests to the Omicron variant of coronavirus, likely reducing treatment options if the new variant prevails.
Two groups of Germany based scientists separately found that protection from GlaxoSmithKline and Vir's antibody cocktail Xevudy held up when exposed to Omicron in lab experiments, but that this was not the case for Lilly's antibodies, bamlanivimab and etesevimab, and the antibodies in Regeneron's Ronapreve drug.
Two groups of Germany based scientists separately found that protection from GlaxoSmithKline and Vir's antibody cocktail Xevudy held up when exposed to Omicron in lab experiments, but that this was not the case for Lilly's antibodies, bamlanivimab and etesevimab, and the antibodies in Regeneron's Ronapreve drug.
12-15-2021, 06:40 AM
#34
Prime Minister/Moderator
Thread Starter
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 40,263
US researchers (associated with Harvard & MIT) report that two dose regimes (one for J&J) are ineffective against omicron; they believe a booster will restore "most" of the efficacy. Oxford University came to a similar conclusion.
https://www.reuters.com/business/hea...ut-2021-12-14/
https://www.reuters.com/business/hea...ut-2021-12-14/
12-18-2021, 06:00 AM
#35
Gets Weekends Off
Joined APC: Nov 2020
Position: Enoch Powell Enthusiast
Posts: 2,312
IF YOU GET COVID:
Here's a HHS link for places to get monoclonal antibody treatments in every state (or at least where it's been recently shipped)
https://protect-public.hhs.gov/pages...s-distribution
Some caveats: the earlier, the better. Some states have treatment protocols that will preclude you from getting the treatment if you wait too long. Early detection is key; the big-D has made it ridiculously easy to get tested.
Take this link to your doctor: most doctors (as are most pilots) are shake-n-bake, follow-the-numbers sorts of professionals. Because that works most of the time. This might be helpful to your doc, however.
Here's a HHS link for places to get monoclonal antibody treatments in every state (or at least where it's been recently shipped)
https://protect-public.hhs.gov/pages...s-distribution
Some caveats: the earlier, the better. Some states have treatment protocols that will preclude you from getting the treatment if you wait too long. Early detection is key; the big-D has made it ridiculously easy to get tested.
Take this link to your doctor: most doctors (as are most pilots) are shake-n-bake, follow-the-numbers sorts of professionals. Because that works most of the time. This might be helpful to your doc, however.
12-18-2021, 06:03 AM
#36
Furloughed Again?!
Joined APC: Aug 2007
Position: Boeing 737
Posts: 4,804
The president of Regeneron was on Neil Tyson's podcast the other day saying that the current monoclonal antibodies were based on the ancestral virus and will need to be modified to work as well on Omicron.
12-18-2021, 06:19 AM
#37
Gets Weekdays Off
Joined APC: Feb 2007
Position: Economy Minus
Posts: 1,053
12-18-2021, 08:13 AM
#38
:-)
Joined APC: Feb 2007
Posts: 7,339
Originally Posted by ZapBrannigan;[url=tel:3337808
3337808[/url]]The president of Regeneron was on Neil Tyson's podcast the other day saying that the current monoclonal antibodies were based on the ancestral virus and will need to be modified to work as well on Omicron.
12-18-2021, 09:29 AM
#39
Furloughed Again?!
Joined APC: Aug 2007
Position: Boeing 737
Posts: 4,804
Even for Omicron? He said there were 35 mutations to the spike protein and made it sound like it was structurally altered enough that their molecule wasn't a good fit anymore.
12-18-2021, 12:14 PM
#40
:-)
Joined APC: Feb 2007
Posts: 7,339
The RBD is still conserved enough across variants to be treated with mAbs from SARS1.
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