Vaccine Development Summary
#121
Gets Weekends Off
Joined APC: Oct 2010
Posts: 675
It wasn’t a criticism, it was simply an illustration. The issue is perception, not fatalities. As of today about 166,000 deaths are attributed to coronavirus. That’s about 14% of the 1.2 million deaths that we were EXPECTED to average during the last five months and about 500 deaths per million from the total population which is a 0.5 deaths per thousand, or 0.05%.
And damn near half of these were in nursing home Or long term care patients which ran a 35% annual death rate even before COVID anyway.
Yet pax are down 70%. This is not just a public health problem, it is a perception problem. As long as people are as scared of this as they are, things aren’t going to get better - certainly not as quickly as they could.
And damn near half of these were in nursing home Or long term care patients which ran a 35% annual death rate even before COVID anyway.
Yet pax are down 70%. This is not just a public health problem, it is a perception problem. As long as people are as scared of this as they are, things aren’t going to get better - certainly not as quickly as they could.
#122
Yeah, why would I want the one with a long safety history, including the knowledge that my body tolerates that type of vaccine well, when I can get the new one that has no safety record, or any record for that matter(mRNA), and has landed several of the trial participants in the hospital?
#123
Line Holder
Joined APC: May 2010
Posts: 62
The good news is that both the Chinese and Russians are already using not-certified trail (or pre-trial) vaccines for some critical workers. So if not the western vaccines, I'd expect some Asian vaccines to get deployed early and often, so you can watch what happens there.
#125
Efficacy and duration TBD. But a step in the right direction. Foreign vaccines might see the most early use simply because they can get to phase 4 sooner. They skipped phase 3, but hey it's their country (won't happen here).
Last edited by rickair7777; 08-11-2020 at 08:33 AM.
#127
Gets Weekends Off
Joined APC: Jan 2018
Posts: 644
I found this article pretty interesting about how mRNA vaccines work because it was written 5 years ago, before politics corrupted everything:
RNA vaccines: a novel technology to prevent and treat disease - Science in the News
I've already heard grumblings that the vaccine will hijack your entire DNA and turn you into Spider Man or a Cronenburg or something. If that were true you could literally give yourself a 'vaccine' to be an NFL lineman or super genius, or both. I'm pretty sure it just programs a few cells to temporarily produce antibodies that give you immunity, kinda similar to all the viruses that infect our cells, change our DNA, and then go away without any permanent effects (I get that it's technically different). But I'm not a biologist.
Either way, I'd be very surprised if you can keep your airline job without taking the vaccine, so let's hope these nerds didn't **** it up.
RNA vaccines: a novel technology to prevent and treat disease - Science in the News
I've already heard grumblings that the vaccine will hijack your entire DNA and turn you into Spider Man or a Cronenburg or something. If that were true you could literally give yourself a 'vaccine' to be an NFL lineman or super genius, or both. I'm pretty sure it just programs a few cells to temporarily produce antibodies that give you immunity, kinda similar to all the viruses that infect our cells, change our DNA, and then go away without any permanent effects (I get that it's technically different). But I'm not a biologist.
Either way, I'd be very surprised if you can keep your airline job without taking the vaccine, so let's hope these nerds didn't **** it up.
#128
Why would you expect that? It took far longer than that for it to be accepted that there was airborne spread of COVID-19. And especially in Russia, where the stats are whatever Putin decides they are.
For that matter, some side effects take a lot longer to make themselves known. Thalidomide was first marketed in 1957 for anxiety and - tragically ironically - for morning sickness. Yet the fact that it was a potent mutagen that caused birth defects was not identified until 1961.
https://www.smithsonianmag.com/smart...ough-24085623/
Prompt discovery of side effects requires a well thought out statistical analysis before the fact. Having skipped phase 3 studies altogether, there is no good indication the Russians will skillfully manage phase 4.
#129
Why would you expect that? It took far longer than that for it to be accepted that there was airborne spread of COVID-19. And especially in Russia, where the stats are whatever Putin decides they are.
For that matter, some side effects take a lot longer to make themselves known. Thalidomide was first marketed in 1957 for anxiety and - tragically ironically - for morning sickness. Yet the fact that it was a potent mutagen that caused birth defects was not identified until 1961.
https://www.smithsonianmag.com/smart...ough-24085623/
Prompt discovery of side effects requires a well thought out statistical analysis before the fact. Having skipped phase 3 studies altogether, there is no good indication the Russians will skillfully manage phase 4.
For that matter, some side effects take a lot longer to make themselves known. Thalidomide was first marketed in 1957 for anxiety and - tragically ironically - for morning sickness. Yet the fact that it was a potent mutagen that caused birth defects was not identified until 1961.
https://www.smithsonianmag.com/smart...ough-24085623/
Prompt discovery of side effects requires a well thought out statistical analysis before the fact. Having skipped phase 3 studies altogether, there is no good indication the Russians will skillfully manage phase 4.
So there's some potential here but I doubt it changes the timeline for approved vaccinations in the west.
#130
The US will not just accept a .rus certification under these circumstances, not even on an emergency basis. If they report great success, I'd expect the US to fully perform whatever trails the russians skipped or short-cutted.
So there's some potential here but I doubt it changes the timeline for approved vaccinations in the west.
So there's some potential here but I doubt it changes the timeline for approved vaccinations in the west.
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